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在患有抑郁症和焦虑障碍的人群中,常见的残疾措施的响应能力和最小的重要差异
Edimansyah Abdin1, Vanessa Seet1, Anitha Jeyagurunathan1
1Research Division, Institute of Mental Health, Singapore, Singapore.
Frontiers in rehabilitation sciences
|May 15, 2025
概括
世界卫生组织残疾评估表2.0 (WHODAS 2.0) 是检测抑郁症和焦虑症患者的有意义功能改善的最响应措施. 这项研究比较了WHODAS 2.0,希恩残疾量表 (SDS) 和社会和职业功能评估量表 (SOFAS).
科学领域:
- 精神病学和心理健康 精神病学和心理健康
- 临床心理学 临床心理学
- 健康 结果 研究 研究 结果
背景情况:
- 抑郁症和焦虑症严重影响患者的功能.
- 常用的残疾措施包括希恩残疾量表 (SDS),世界卫生组织残疾评估表2.012项版本 (WHODAS 2.0),以及社会和职业功能评估量表 (SOFAS).
- 对比这些措施的响应能力和最小重要差异 (MID) 对临床实用性至关重要.
研究的目的:
- 为了比较WHODAS 2.0,SDS和SOFAS在患有抑郁和焦虑障碍的患者中的响应能力.
- 在同一患者群体内,为这三个残疾指标确定最小重要差异 (MID).
主要方法:
- 总共包括308名患有抑郁症和焦虑症的门诊患者.
- 所有参与者在两个评估点完成了WHODAS 2.0,SDS和SOFAS.
- 使用三角测量估计了最小重要差异 (MID);使用标准化响应平均值 (内部) 和接收器运行特征曲线 (外部) 评估了响应性.
主要成果:
- 最好的MID估计为WHODAS 2.0的3分,SDS的4分,SOFAS的6分.
- 这三种措施都显示出对患者健康问卷-8和通用焦虑障碍-7得分的变化有良好的内部反应.
- 所有措施的外部响应性都足够 (AUC ≥ 0.7),但当MID被纳入改进标准时,只有WHODAS 2.0保持了足够的响应.
结论:
- 对于检测抑郁和焦虑患者的功能改善,WHODAS 2.0表现出卓越的响应能力,特别是在考虑最小重要的差异时.
- 这些发现为临床医生在监测患者的功能和确保有效的临床管理方面提供了宝贵的指导.
- 该研究强调了选择适当的残疾措施的重要性,以准确评估治疗结果.
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