关注哈萨克斯坦生育技术后出生的儿童的内分泌系统
Sevara Ilmuratova1, Lyazzat Manzhuova2, Aigul Bazarbayeva2
1Department of Science and Consulting, Kazakhstan Medical University KSPH, Almaty, Republic of Kazakhstan.
Qatar medical journal
|May 15, 2025
概括
辅助生殖技术 (ART) 不会改变后代的内分泌或生化特征. 虽然ART儿童的甲状腺激素和水平略有差异,但这些水平保持在正常范围内,证实了ART的安全性.
科学领域:
- 内分泌学 在内分泌学.
- 生殖医学 生殖医学
- 儿科 儿科 儿科
背景情况:
- 由于分娩延迟,辅助生殖技术 (ART) 的使用越来越多.
- 不孕症影响了很大一部分夫妇,其中很大一部分出生是体外受精 (IVF) 的结果.
- 对ART对后代荷尔蒙和人类指标的影响需要进一步研究.
研究的目的:
- 将通过ART怀孕的儿童的荷尔蒙和人体数据与自然怀孕的儿童进行比较.
- 评估各种ART方法对后代内分泌和生化参数的影响.
主要方法:
- 一项队列研究,比较通过ART怀孕的儿童 (实验组) 与自然怀孕的儿童 (对照组).
- 生物化学分析包括自由三甲状腺素 (T3),总甲状腺素 (T4),胰岛素,胰岛素类生长因子,葡萄糖,和.
- 对两组人群收集人体测量数据 (体重,身高).
主要成果:
- ART没有显著改变甲状腺内分泌面板或其他生化参数.
- 特定的ART变异 (IVF,胚胎移植,ICSI) 对测量指标没有影响.
- 自然孕育的孩子出生时体重和身高较高;ART儿童的自由T3,和葡萄糖水平略高,均在正常参考范围内.
结论:
- 使用ART似乎不会对后代的内分泌和生化特征产生负面影响.
- 确定了某些生化和人体标志物之间的相关性,需要进一步研究.
- 目前的数据支持各种辅助生殖技术的安全性.
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