多药,潜在不合适的药物,器官功能和2型糖尿病老年患者的生活质量之间的关系
Hozan Jaza Hama Salh1, Tavga Ahmed Aziz1, Taha Othman Mahwi1
1University of Sulaimani, Sulaimani, Kurdistan Region, Iraq.
多药性在2型糖尿病的老年人中很常见,导致更多的潜在不适当药物 (PIM) 和药物相互作用 (DDI). 这种做法与生活质量下降有关,强调需要仔细管理药物.
科学领域:
- 老年病的医生 老年病的医生
- 临床药房 临床药房
- 内分泌学 在内分泌学.
背景情况:
- 多药在老年人中普遍存在,特别是那些患有2型糖尿病 (T2DM) 等慢性疾病的人.
- 识别可能不合适的药物 (PIM) 和药物相互作用 (DDI) 对患者的安全和结果至关重要.
研究的目的:
- 评估老年T2DM患者中多药,PIM和严重DDI的患病率.
- 检查多药与PIM,DDI,功能,肝功能,电解质和生活质量 (QoL) 之间的关联.
主要方法:
- 一项涉及伊拉克苏莱曼尼136名老年T2DM患者的横截面研究.
- 通过采访,问卷和实验室测试 (HbA1c,葡萄糖,肌,尿素,AST,ALT,) 收集的数据.
- 使用STOPP标准v3识别的PIM;使用Medscape交互数据库评估的DDI.
主要成果:
- 多药性患病率为55.88%,与更高的BMI,更长的糖尿病持续时间,更多的并发症和并发症相关.
- PIM (64.7%) 和严重的DDI (14%) 是常见的,多药房患者的发病率更高 (PIM 73.7%,DDI 25%).
- 多药性与较低的QOL分数和较高的血清相关,但与或肝功能测试无关.
结论:
- 在具有多种药物的老年T2DM患者中存在PIM和严重DDI的高患病率.
- 多药与这种人群的生活质量低下有关.
- 对于经历多药的老年T2DM患者来说,定期的药物检查和管理是必不可少的.
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