输血依赖性沙拉西米亚患者的眼科表现谱
Pragya Jain1, Sadaf Ikram2, Yuri Kashiv3
1Ophthalmology, People's College of Medical Sciences and Research Centre, Bhopal, IND.
Cureus
|May 15, 2025
概括
眼科问题在血病患者中很常见,76%的患者患有折射错误和血管变化等疾病. 定期的眼科检查对于早期检测和在输血依赖性沙拉西米亚 (TDT) 患者的视力保护至关重要.
科学领域:
- 眼科医生 眼科 眼科
- 血液学 血液学 血液学
- 遗传学 是一个遗传学.
背景情况:
- thalassemia是一种遗传性血液疾病,需要定期输血,导致诸如铁过载等并发症.
- 这些并发症显著增加了患者出现各种眼科症状的风险.
- 了解这些眼部问题对于管理患者健康至关重要.
研究的目的:
- 为了确定输血依赖性沙拉西米亚 (TDT) 患者眼科异常的患病率.
- 探索眼部发现与血清费里丁,血红蛋白和化疗持续时间等因素之间的相关性.
主要方法:
- 一项涉及50名患有β-thalassemia major的儿科患者 (年龄在1-15岁) 的横截面研究.
- 进行了全面的眼科检查,包括视力敏度,眼底镜和裂灯检查.
- 收集了病史,输血频率和化疗法的数据.
主要成果:
- 76%的TDT患者表现出一种或多种眼部表现.
- 折射误差 (56%) 和血管扭曲 (32%) 是最常见的发现.
- 还观察到颜色异常和视盘.
结论:
- 眼科症状在TDT患者中非常普遍.
- 定期的眼科评估对于早期发现并发症和管理并发症至关重要.
- 建议采用涉及血液学家和眼科医生的跨学科方法,以改善患者的生活质量和保持视力.
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