在接受抗逆转录病毒治疗的成年人中,抑郁症及其预测因素
Azizat A Lebimoyo1, Mumtaz Sanni2, Mujeedat A Hassan3
1Psychiatry, Lagos State University Teaching Hospital, Lagos, NGA.
Cureus
|May 15, 2025
概括
抑郁症影响了超过一半的艾滋病毒/艾滋病成年人,未婚,女性和缺乏社会支持是关键的风险因素. 早期识别和干预对于改善这一群体的健康结果至关重要.
科学领域:
- 医学研究 医学研究
- 精神病学是一个精神病学.
- 公共卫生 公共卫生
背景情况:
- 抑郁症是艾滋病毒/艾滋病成年人的重要并发症,影响治疗坚持和健康结果.
- 包括临床,治疗相关和社会人口统计方面的上下文因素有助于艾滋病毒阳性个体的抑郁病原体.
- 了解抑郁症患病率和预测因素对于制定预防策略和改善艾滋病毒阳性成年人的护理至关重要.
研究的目的:
- 为了确定接受抗逆转录病毒治疗的HIV阳性成年人中抑郁症的患病率.
- 在这个患者群体中确定与抑郁症相关的预测因素.
主要方法:
- 一项涉及257名艾滋病毒阳性成年人的横截面研究,在尼日利亚的血液学诊所进行.
- 系统的随机抽样被用于参与者选择.
- 数据采用患者健康问卷 (PHQ-9),莫里斯基药物坚持度表 (MMAS-4) 和社会支持/人口统计问卷收集;使用单变量,双变量和多变量方法分析.
主要成果:
- 在研究参与者中,发现抑郁症的患病率为54%.
- 抑郁症的重要预测因素包括未婚 (OR=10.9),女性性别 (OR=5.8) 和低社会支持 (OR=11.2).
- 失业率也是一个预测因素,虽然保护性 (OR=0.2).
结论:
- 抑郁症在艾滋病毒阳性成年人中非常普遍,并受到临床,社会和人口因素的结合的影响.
- 这些已识别的因素需要在抗逆转录病毒诊所的患者护理中加以考虑,以提高治疗预后.
- 建议对易患抑郁症的HIV阳性成年人进行进一步的研究,特别是干预研究.
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