在癌症成像档案中对非图像数据的本体学增强表示
Jonathan P Bona1, Tracy S Nolan1, Mathias Brochhausen1
1Department of Biomedical Informatics, University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States.
CEUR workshop proceedings
|May 15, 2025
概括
癌症成像档案 (TCIA) 现在集成了使用开放生物医学本体学的各种非图像癌症研究数据. 这提高了研究癌症的研究人员的可访问性和可用性.
科学领域:
- 生物医学信息学 生物医学信息学
- 放射学 放射学是一门学科.
- 癌症研究 癌症研究
背景情况:
- 癌症成像档案 (TCIA) 为研究提供了超过1100万张未识别的癌症相关医学图像.
- 根据疾病,模式或研究重点,TCIA将数据组织成DICOM格式的放射学集合.
- 许多TCIA收藏包含多样化的非图像数据集,缺乏标准化表示,阻碍了可访问性.
研究的目的:
- 提高TCIA内部各种非图像数据集的可访问性和可用性.
- 将非图像数据转化为集成的语义表示,使用开放的生物医学本体 (OBOs).
- 为了记录挑战,并展示精选的TCIA数据集的详细语义表示.
主要方法:
- 应用开放的生物医学本体学,以语义地表示多样化的非图像数据.
- 开发了一种共同的方法来整合和标准化各种数据格式.
- 分析和记录了在精选的TCIA收藏中遇到的数据表示挑战.
主要成果:
- 成功地将异质的非图像数据集转化为集成的语义表示.
- 证明了使用OBOs用于标准化各种癌症研究数据的可行性.
- 确定并详细说明在TCIA中表示非图像数据的具体障碍.
结论:
- 使用OBOs的语义集成显著提高了TCIA中非图像数据的可访问性和可用性.
- 标准化表示方便更强大的数据分析和研究重复使用.
- 解决数据表示挑战对于最大限度地提高综合研究档案的价值至关重要.
更多相关视频
12:23Multi-modal Imaging of Angiogenesis in a Nude Rat Model of Breast Cancer Bone Metastasis Using Magnetic Resonance Imaging, Volumetric Computed Tomography and Ultrasound
Published on: August 14, 2012
14.2K
07:14Three-Dimensional Imaging of Tumor-Bearing Tissue Using the Iterative Bleaching Extends Multiplexity Approach
Published on: April 25, 2025
63
相关概念视频
01:29Positron Emission Tomography
3.9K
Positron emission tomography (PET) is a medical imaging technique involving radiopharmaceuticals — substances that emit short-lived radiation. Although the first PET scanner was introduced in 1961, it took 15 more years before radiopharmaceuticals were combined with the technique and revolutionized its potential.
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body...
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body...
3.9K
01:24X-ray Imaging
5.2K
German physicist Wilhelm Röntgen (1845–1923) was experimenting with electrical current when he discovered that a mysterious and invisible "ray" would pass through his flesh but leave an outline of his bones on a screen coated with a metal compound. In 1895, Röntgen made the first durable record of the internal parts of a living human: an "X-ray" image (as it came to be called) of his wife’s hand. Scientists worldwide quickly began their own experiments with...
5.2K
02:43Mouse Models of Cancer Study
5.5K
Mice have long served as models for studying human biology and pathology because of their phylogenetic and physiological similarity with humans. They are also easy to maintain and breed in the laboratory, and hence, many inbred strains are now available for research. Studies on mice have contributed immeasurably to our understanding of cancer biology.
The development of transgenic, knockout, and knock-in mice has led to an exponential increase in their use as model organisms in research,...
The development of transgenic, knockout, and knock-in mice has led to an exponential increase in their use as model organisms in research,...
5.5K
02:49Cancer Therapies
7.5K
Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
7.5K
01:10Computed Tomography
4.2K
Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
4.2K