没有破裂的内动脉瘤的自然过程:在中国的一项病例监测研究
Xiuhu An1, Linchun Huan2, Pengran Liu1
1Department of Neurosurgery, Tianjin Medical University General Hospital, Tianjin, China.
Frontiers in neurology
|May 15, 2025
概括
中国患者对未破裂的内动脉瘤 (UIA) 手术的意愿较低,增加了破裂风险. 晚年和更大的动脉瘤大小是中国UIA破裂的关键风险因素.
科学领域:
- 神经外科 神经外科
- 血管神经学 血管神经学
- 公共卫生 公共卫生
背景情况:
- 在中国对未破裂的内动脉瘤 (UIA) 进行了有限的大规模研究.
- 需要了解中国人口特有的自然过程和风险因素.
研究的目的:
- 描述中国UIA的现状.
- 为了确定UIA破裂的主要风险因素.
- 为临床决策提供数据.
主要方法:
- 对来自中国北部12个中心的1337名UIA患者 (2017-2020年) 的回顾性研究.
- 平均随访时间为3.1年.
- 使用考克斯比例危险模型和卡普兰-梅尔曲线分析破裂风险因素.
主要成果:
- 每年的UIA破裂率为1.75%.
- 破裂的危险因素:年龄>70岁,动脉瘤大小10-20毫米和≥20毫米.
- 内动脉 (ICA) 的位置是一个保护因素.
结论:
- 中国独特的治疗模式包括手术接受率低,导致破裂率更高.
- 高龄,动脉瘤大小和位置对于UIA破裂风险至关重要.
- 调查结果为临床实践,公共卫生政策和患者对中国UIA的认识提供了信息.
相关概念视频
Aneurysm I: Introduction
An aortic aneurysm is a localized outpouching or dilation at a weak point in the artery wall. It may involve different parts of the aorta, such as the abdominal aorta, aortic arch, or thoracic aorta.Etiological factorsSeveral disorders are associated with aortic aneurysms.Congenital causes, such as primary connective tissue disorders like Marfan syndrome, impact the integrity and strength of connective tissues, notably affecting the aorta. Marfan syndrome is a genetic disorder that specifically...
Aneurysm II: Clinical Manifestations and Diagnostic Studies
Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
Aneurysm III: Interprofessional Care
Aneurysm management involves either conservative medical therapy or surgical intervention, depending on the size and symptoms of the aneurysm. Conservative management is generally reserved for smaller, asymptomatic aneurysms, while larger or symptomatic aneurysms often necessitate surgical repair.Conservative Medical TherapyFor small, asymptomatic aneurysms, particularly abdominal aortic aneurysms (AAA) less than 5.5 centimeters in diameter, conservative medical therapy is recommended. This...


