神经外科手术中的抗生素消耗与尾切除:呼吁采取抗生素管理倡议
Rika Yulia1, Steven Victoria Halim1, Fauna Herawati1
1Departement of Clinical and Community Pharmacy, Faculty of Pharmacy, University of Surabaya, East Java, Indonesia.
Medicine and pharmacy reports
|May 15, 2025
概括
与尾切除相比,在选择性神经外科手术中,预防性抗生素的使用率更高. 监测抗生素消费对于预防细菌耐药性和制定抗生素管理计划至关重要.
科学领域:
- 传染性疾病 传染性疾病
- 药理学 药理学是指药理学的学科.
- 手术感染 手术感染
背景情况:
- 手术部位感染 (SSI) 是全球主要的健康问题,特别是在印度尼西亚.
- 预防性抗生素对于预防SSI和降低死亡率至关重要.
- 建议在高风险的手术中进行抗生素预防,包括长期干净和干净污染的手术.
研究的目的:
- 为了分析预防性抗生素消费量.
- 为了比较神经外科和尾切除术之间的抗生素消耗.
主要方法:
- 使用来自两个苏拉巴亚医院的医疗记录进行的观察性研究.
- 分析神经外科和尾切除患者的抗生素消耗情况.
- 抗生素使用量化定义每日剂量 (DDD) 每100个病床日.
主要成果:
- 选择性神经外科手术的抗生素消耗量 (47.43 DDD/100 个睡日) 比选择性 (21.26 DDD/100 个睡日) 和紧急尾切除 (76.34 DDD/100 个睡日) 高.
- 频繁使用的是诸如cefixime和ceftriaxone之类的宽谱抗生素.
- 在尾切除手术中, ceftriaxone 和 metronidazole 是常见的,在紧急情况下使用率更高.
结论:
- 预防性抗生素消耗是一个重大问题.
- 评估和监测抗生素的使用对于制定抗细菌耐药性的策略至关重要.
- 实施抗生素管理计划对于优化抗生素使用至关重要.
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