系统性红斑狼患者的COVID-19后心理状况:一个前性观察性研究
Jingyi Wu1, Lijuan Zhang2, Zhuochao Zhou1
1Department of Rheumatology and Immunology, Ruijin Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Clinical and experimental rheumatology
|May 15, 2025
概括
患有COVID-19的全身性红斑狼 (SLE) 患者经历了更糟糕的心理状况,包括疲劳和抑郁症. 建议对这些患者进行早期查和向治疗.
科学领域:
- 类风湿病学 类风湿病学
- 传染性疾病 传染性疾病
- 精神病学是一个精神病学.
背景情况:
- 系统性红斑狼 (SLE) 是一种自身免疫性疾病,可以影响多个器官.
- COVID-19对SLE等慢性病患者的心理影响尚不清楚.
- 了解COVID-19对SLE患者的长期心理影响对于他们的整体健康管理至关重要.
研究的目的:
- 评估SLE患者在COVID-19感染后的心理健康状况.
- 在COVID-19后的SLE患者中调查各种精神症状之间的相互关系.
- 在受影响患者的心理痛苦网络中识别核心和桥梁症状.
主要方法:
- 一项观察性研究涉及619名SLE患者 (493名COVID-19阳性,126名未感染).
- 使用经过验证的尺度 (VAS,MFI,PHQ-9,PSQI) 评估疼痛,疲劳,抑郁和睡眠质量.
- 网络分析以确定中心和连接的精神症状;物流回归以确定COVID-19症状影响.
主要成果:
- 感染COVID-19的SLE患者报告了明显增加的疼痛,一般疲劳,抑郁症 (PHQ-9) 和睡眠障碍 (PSQI).
- 一般疲劳和"感到丧,绝望"被确定为心理网络中的核心症状.
- "睡眠困难"",一般性疲劳"和"白天功能障碍"成为重要的桥梁症状.
- 特定的COVID-19症状如呼吸短促,虚弱和关节疼痛与随后的心理痛苦相关.
结论:
- COVID-19感染与SLE患者的长期心理状况较差有关.
- 这些发现强调了在COVID-19后SLE患者进行主动心理健康查的必要性.
- 制定有针对性的干预措施对于减轻这一脆弱群体的心理负担至关重要.
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