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骨质合体移植和自身移植用于大腿骨头缺陷:一个多中心研究
Sean C Clark1, Christopher V Nagelli1, Anthony DeNovio1
1Department of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota, USA.
The American journal of sports medicine
|May 15, 2025
概括
对于大腿骨头缺陷的骨髓移植显示出有利的结果. 所有移植和自移植选项都有效,具有相似的结果和较低的转换率到全关节整形术 (THA).
科学领域:
- 整形外科 整形外科 整形外科
- 再生医学是一种再生医学.
- 运动医学 运动医学
背景情况:
- 腿部头部缺陷需要治疗以解决软骨和下地骨损伤.
- 骨髓合移植和自身移植正在成为年轻患者可行的手术选择.
研究的目的:
- 评估骨质突合移植与自移植移植对大腿骨头缺陷的临床和放射性结果.
- 确定转换到全关节整形术 (THA) 的风险因素.
主要方法:
- 两所机构27名患者的回顾性病例系列 (证据水平,4).
- 使用mHHS,HOS-ADL,HOS-SSS和iHOT-12评估的临床结果.
- 使用Tönnis分级进行骨关节炎的放射评估.
主要成果:
- 股骨头全移植和非正位体股骨囊全移植之间临床结果没有显著差异.
- 整体移植队列:21.1%转换为THA;6.7%的放射性骨关节炎进展.
- 自体移植队列:没有转换到THA.
结论:
- 骨髓合移植和自身移植移植为股骨头缺陷提供了有利的结果.
- 非正位体的股骨状合体移植产生了与股骨头移植相似的结果.
- 这两种移植类型都适合用于焦点股骨头缺陷的考虑.
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