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Updated: May 16, 2025

Tumor Engraftment in a Xenograft Mouse Model of Human Mantle Cell Lymphoma
10:52

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Published on: March 30, 2018

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连续BTKi和venetoclax治疗的地幔细胞淋巴瘤中的抵抗机制和克隆动力学

Tamás László1,2, László Imre Pinczés3,4, Bence Bátai1,2,5

  • 1HCEMM-SE Molecular Oncohematology Research Group, Department of Pathology and Experimental Cancer Research, Semmelweis University, Budapest, Hungary.

The Journal of pathology
|May 15, 2025
PubMed
概括

这项研究揭示了导致地幔细胞淋巴瘤 (MCL) 对向疗法的耐药性的遗传因素. 了解这些机制对于改善接受布鲁顿氨酸激酶抑制剂 (BTKi) 和venetoclax的复发性MCL患者的治疗结果至关重要.

关键词:
耐药性 耐药性 耐药性 耐药性 耐药性地毯细胞淋巴瘤这是下一代测序.有针对性的治疗.维尼托克拉克斯的耐药性

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