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Updated: May 16, 2025

Back Mechanical Sensitivity Assessment in the Rat for Mechanistic Investigation of Chronic Back Pain
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Back Mechanical Sensitivity Assessment in the Rat for Mechanistic Investigation of Chronic Back Pain

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慢性下背痛中的周水道灰色:神经递质和功能调节失调

Laura Sirucek1,2,3, Iara De Schoenmacker2,4,5, Lindsay Mary Gorrell1

  • 1Department of Chiropractic Medicine, Balgrist University Hospital, University of Zurich, Zurich, Switzerland.

Pain
|May 15, 2025
PubMed
概括

患有慢性腰部疼痛的患者在周水道灰色 (PAG) 中表现出大脑化学变化,谷氨酸减少,GABA增加. 这种不平衡可能会损害疼痛调节,并导致慢性疼痛疾病.

关键词:
大脑干的大脑干慢性疼痛是一种慢性疼痛.下降疼痛调制的调节.激发性/抑制性的平衡.对于GABA来说,这是一个很好的选择.谷氨酸酸盐的使用方法磁共振光谱学 磁共振光谱学

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