解读呼吸系统护理中的不良药物反应:印度一家三级医院的前性预测和严重性分析
Vaishnavi V Gaonkar1, Vinay V Shanbhag1, Mandati Santhosh Reddy1
1Department of Pharmacy Practice, KLE College of Pharmacy, Belagavi, KLE Academy of Higher Education and Research, Karnataka.
概括
药物不良反应 (ADR) 在老年呼吸系统患者中很常见,大多数是轻微和可预见的. 改善药物监测和报告对于患者安全和更好的治疗结果至关重要.
科学领域:
- 药物监督 药物监督 药物监督
- 临床药房 临床药房
- 呼吸系统医学 呼吸系统医学
背景情况:
- 药物不良反应 (ADRs) 给医疗保健带来了重大挑战,包括增加发病率,长时间住院和增加成本.
- 糟糕的ADR报告,特别是在印度等发展中国家,阻碍了有效的患者安全计划.
- 监测不良反应是必不可少的,特别是对于脆弱的患者群体,如患有慢性呼吸道疾病的老年人.
研究的目的:
- 评估第三级护理医院呼吸系患者的副作用的严重程度,可预测性和因果关系.
- 在这个患者群体中确定常见的ADR模式和干预措施.
- 强调印度需要加强药物监管战略的需要.
主要方法:
- 从2023年9月到2025年1月进行了前性观察研究.
- 包括45岁及以上患有慢性呼吸道疾病的患者.
- 使用经过验证的尺度 (WHO-Uppsala,Hartwig和Siegel,可预测性评估) 和描述性统计数据进行分析.
主要成果:
- 在107名患者中,63.5%是老年人,59.8%是女性.
- 轻微的ADR占60.7%,严重的ADR为3.7%.
- 77.5%的副作用是可预见的,胃肠道 (33.6%) 和呼吸道 (18.6%) 疾病是最常见的. 因果关系是可能的 (51.4%) 或可能的 (37.3%).
结论:
- 这项研究强调了老年呼吸系统患者中可预见的副作用的高患病率.
- 印度急需改善药物监测计划和ADR报告系统.
- 提高预测性评估和报告可以显著提高患者的安全性和治疗疗效.
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