便失禁混合便秘的临床特征和病理生理学 (FI-MC):一个未被认可的问题
Busra Inal1,2, Yun Yan1, Abeer Aziz1
1Division of Neurogastroenterology/Motility, Wellstar MCG Health Medical Center, Augusta University, Augusta, GA, USA.
The American journal of gastroenterology
|May 15, 2025
概括
与慢性便秘 (CC) 结合的便失禁 (FI) 与单独的FI相比,具有不同的临床特征和病理生理学. 识别这些表型可以改善患者管理.
科学领域:
- 胃肠病学 胃肠病学
- 结肠直肠手术 结肠直肠手术
- 盆地底疾病 盆地底疾病
背景情况:
- 便失禁 (FI) 和慢性便秘 (CC) 通常被单独诊断,但许多患者都经历了这两种情况.
- 混合FI和CC (FI-MC) 的独特临床和病理生理特征仍然不清楚.
研究的目的:
- 调查FI-MC.的临床和病理生理特征.
- 为了比较FI-MC患者与那些单独经历FI和健康对照的人.
主要方法:
- 一项回顾性研究设计,比较了165名FI-MC患者,184名FI单独患者和31名健康对照.
- 使用了肠道症状问卷,门测量,气球驱逐测试,神经生理学和门超声波.
主要成果:
- 与FI单独的患者相比,FI-MC患者报告了比FI单独的患者更高的压力,不完全的疏散,疼痛,胀气,数字机动和淋浴术的患病率.
- 与FI-MC和对照组相比,FI患者的门静止压力较低. 两组FI都减少了门挤压压力和延长了神经传导时间.
- 异能排便在FI-MC中更为普遍,而关节缺陷在FI单独组中更为常见.
结论:
- 便失禁患者可以分为两个不同的表型:单独FI和FI与慢性便秘 (FI-MC).
- 每种表型都表现出独特的临床特征和潜在的病理生理学.
- 识别这些独特的表型对于优化便失禁的管理至关重要.
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