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Updated: May 16, 2025

3D Culturing of Organoids from the Intestinal Villi Epithelium Undergoing Dedifferentiation
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UTX (KDM6A) 在体内自我更新表皮质中促进非催化差异化

Gina N Pacella1,2, Nina Kuprasertkul1,2, Lydia Bao1,2

  • 1Department of Dermatology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104.

Proceedings of the National Academy of Sciences of the United States of America
|May 15, 2025
PubMed
概括

组织素脱甲基酶UTX (KDM6A) 调节皮肤细胞分化和视网酸信号传递. 它的缺失会影响皮肤平衡,特别是在女性身上,突出了皮肤疾病的新表观遗传标.

关键词:
不同化的差异化差异化.表观遗传学是指表观遗传学.视网体信号传递性偏见的性别偏见皮肤生物学 皮肤生物学

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