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Updated: May 17, 2025

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GATA3通过指2-调节相分离方式对转录组进行差异调节

Yatao Chen1, Yajie Wan2, Xiaoying Pei2

  • 1Jiangsu Cancer Hospital, Jiangsu Institute of Cancer Research, Affiliated Cancer Hospital of Nanjing Medical University, Nanjing 210009, China; Department of Biochemistry, School of Life Sciences, Nanjing Normal University, Nanjing 210023, China; Hangzhou Institute of Medicine, Chinese Academy of Sciences, Hangzhou 310022, China.

Cell reports
|May 15, 2025
PubMed
概括

DNA结合域调节转录因子相分离以控制基因. GATA3突变影响阶段分离,改变基因表达,影响乳腺癌预后和瘤生长.

关键词:
科普:分子生物学 分子生物学的DNA结合域域.在 GATA3 和 GATA3 之间.乳腺癌 乳腺癌 乳腺癌不同调节的转录组.与雌激素α相关的基因表达.与免疫相关的基因表达.阶段分离的分离阶段分离.转录因子的转录因子手指的指是什么意思

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