与口腔癌手术后并发症相关的因素:前性研究
Paulo Victor Sola Gimenes1, Daniel Abreu Rocha1, Marco Aurélio Vamondes Kulcsar2
1Universidade de São Paulo (USP), Faculdade de Medicina (FM), Hospital das Clínicas (HC), São Paulo, SP, Brazil.
Brazilian journal of otorhinolaryngology
|May 15, 2025
概括
瘤厚度超过10mm和肌肉皮膜重建增加了口腔癌手术中的术后并发症. 识别这些风险因素有助于更好的患者管理和结果.
科学领域:
- 在瘤学瘤学.
- 手术瘤学手术瘤学
- 头部和部手术 头部和部手术
背景情况:
- 头部和部癌症手术,特别是口腔恶性瘤手术,存在严重的术后并发症风险.
- 有效的管理需要确定预外科预测术后不良事件的术前因素.
研究的目的:
- 在接受口腔癌手术治疗的患者中,确定与术后并发症相关的术前预后因素.
- 加强风险分层,并为口腔状细胞癌的手术规划提供信息.
主要方法:
- 这是一项前性研究,涉及43名患有口腔状细胞癌的患者,他们正在接受治疗性手术治疗.
- 数据收集的重点是手术前因素和手术后并发症,直至手术后30天.
- 统计分析,包括多变量逻辑回归,用于确定显著预测因素.
主要成果:
- 17名患者 (约40%) 经历了术后并发症,其中17.6%需要重新手术.
- 常见的并发症包括痕脱光和手术部位感染.
- 确定的显著预测因素是瘤厚度>10mm (p=0.002) 和肌皮膜重建 (p<0.001). 滥用酒精,pT4a瘤和mGPS得分也显示了相关性.
结论:
- 瘤厚度大于10mm是口腔癌手术中术后并发症的关键预测因素.
- 用肌皮片进行重建也与增加并发症风险显著相关.
- 这些发现突出了手术前风险评估和手术决策的关键因素.
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