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Updated: May 17, 2025

The bm12 Inducible Model of Systemic Lupus Erythematosus SLE in C57BL/6 Mice
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升高的转激素受体1促进B细胞自身免疫在全身性红斑狼

Tohtihan Alim1, Bin Yang1, Yaqi Zhang2

  • 1Department of Rheumatology and Immunology, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China.

International immunopharmacology
|May 15, 2025
PubMed
概括

收费类受体7 (TLR7) 调节B细胞中的转移素受体1 (TFR1),促进自身免疫力,并通过增加活性氧物种 (ROS) 来促进全身性红斑狼 (SLE). 这项研究强调了TFR1作为SLE的潜在治疗点.

关键词:
乙型淋巴细胞B型淋巴细胞系统性红血性狼 (Systemic lupus erythematosusus) 是一种全身性狼.收费类受体 7 收费类受体 7转移氨酸受体1 转移氨酸受体1

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