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食白补充剂对肠道发育和 brojlers 模式识别受体 (PRRs) 的基因表达的影响

Xue Pan¹, Jie He², Okasha Hamada³

¹College of Food Science and Engineering, Shandong Agricultural University, Taian, Shandong 271018, PR China; Key Laboratory of Efficient Utilization of Non-Grain Feed Resources, College of Animal Science and Technology, Shandong Agricultural University, Taian, Shandong 271018, PR China.

Poultry science

|May 15, 2025

概括

食白补充剂改善了 brojler 的生长性能和肠道发育. 氨酸还通过以特定组织的方式影响模式识别受体基因表达来调节免疫反应.

科学领域:

动物营养动物营养
禽畜科学禽畜科学禽畜科学
免疫学免疫学免疫学

背景情况:

氨酸 (Leu) 是一种必不可少的氨基酸,对蛋白质合成和代谢信号传递至关重要.
了解Leu在调节免疫反应和肉生长中的作用对于优化料策略至关重要.

研究的目的:

研究食白补充剂对肉生长,肠道发育,尸体特征和模式识别受体 (PRR) 基因表达的影响.
评估白素作为家禽免疫调节性料添加剂的潜力.

主要方法:

144个Arbor Acres肉被养为基底饮食 (CON) 或基底饮食,其中含有0.4%的素.
增长表现,内脏器官指数,尸体特征,肠道生长以及TLR2,TLR4,NOD1,NOD5和IL-4的mRNA水平在20天和40天被评估.
进行了统计分析,以确定治疗组之间的显著差异.

主要成果:

素补充剂使料转换率 (FCR) 从1-20天降低,平均每日增益 (ADG) 从21-40天增加.
素增强了肠道的相对重量和长度,并在20天后增加了十二指肠和十足肠中的IL-4表达.
20天后,白氨酸降低了十二指肠中的NOD1,NOD5和TLR4基因表达和阴中的NOD1. 在40天后,氨酸增加了胸肌的产量,并降低了胸肌中的TLR4.

结论:

食白补充剂对肉生长性能和肠道发育产生积极影响.
氨酸以组织特定的方式调节与PRR相关的免疫反应,这表明它在免疫调节中的作用.
氨酸显示出作为 brojlers 的有效免疫调节料添加剂的潜力.

关键词:

肉牛肉是什么意思肠道肠道肠道氨酸 (Leucine) 是一种蛋白质.肌肉肌肉肌肉肌肉模式识别受体的模式识别受体

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