在里曼的多元体上对大脑功能连接的动态和低维建模
Mingyu Wang1, Yueming Wang2, Yuxiao Yang3
1MOE Frontier Science Center for Brain Science and Brain-machine Integration, Zhejiang University, Hangzhou, China; Nanhu Brain-computer Interface Institute, Hangzhou, China; School of Computer Science and Technology, Zhejiang University, Hangzhou, China.
NeuroImage
|May 15, 2025
概括
这项研究引入了一种新的里曼纳状态空间模型 (RSSM),以有效地在里曼纳多重体上模拟时间变化的大脑功能连接 (FC). 新的框架准确地预测了FC动态,并有助于分类情绪状态.
科学领域:
- 神经科学是一个神经科学.
- 数据科学数据科学数据科学
- 数学 数学 是一个数学.
背景情况:
- 大脑功能连接 (FC) 建模对于理解大脑功能和功能障碍至关重要.
- FC通常以对称正定数 (SPD) 矩阵表示在里曼的多元体上,这带来了独特的建模挑战.
- 现有的方法在里曼几何中与FC矩阵时间序列的时间动态,随机性和高维度作斗争.
研究的目的:
- 开发一个统一的里曼纳状态空间建模框架,以应对建模FC矩阵时间序列的挑战.
- 为了使SPD里曼纳式多元体上FC的动态,随机和低维建模.
- 改进FC时间序列的预测和大脑状态的分类.
主要方法:
- 构建了一个新的里曼纳状态空间模型 (RSSM) 与一个隐藏的SPD矩阵状态.
- 开发了一种瑞曼粒子波器 (RPF),用于估计隐藏状态和预测FC时间序列.
- 引入了一个利曼预期最大化 (REM) 算法,用于适应RSSM参数.
主要成果:
- 拟议的RSSM框架成功地模拟了SPD的Riemannian模组上的动态,随机和低维FC矩阵时间序列.
- 里曼粒子波器 (RPF) 准确估计隐藏状态并预测FC时间序列.
- 里曼的预期最大化 (REM) 算法有效地符合模型参数.
结论:
- 开发的里曼纳状态空间建模框架 (RSSM,RPF,REM) 有效地解决了建模大脑功能连接的关键挑战.
- 该框架能够准确预测EEG FC时间序列和分类情绪状态,优于传统的欧几里德方法.
- 这项工作对推进使用里曼几何学用于FC建模的大脑功能和功能障碍的研究具有重要意义.
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