抑郁症和湿性过活膀之间的肥胖中介关联:从2005年到2020年的结果 NHANES
Jiahao Zhang1, Shuqiang Huang2, Chuxian Hu3
1Department of Urology, The Eighth Affiliated Hospital, Sun Yat-sen University, Shenzhen, Guangdong, 518033, China.
Obesity research & clinical practice
|May 15, 2025
概括
较高的抑郁水平会增加湿过活性膀 (wet-overactive bladder, wet-OAB) 的风险,特别是在肥胖的人群中. 肥胖部分调解了这种关系,突出了对湿OAB患者的心理健康和体重管理干预措施的需要.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 精神病学是一个精神病学.
- 公共卫生 公共卫生
背景情况:
- 抑郁症,肥胖和潮湿过活性膀 (wet-OAB) 之间的关系需要进一步的全面调查.
- 湿OAB是一种影响生活质量的常见疾病,通常与心理健康问题和肥胖症并发.
研究的目的:
- 调查抑郁水平与湿OAB风险之间的关联.
- 检查一般和腹部肥胖在抑郁-湿-OAB关系中的调解作用.
主要方法:
- 这是一项横截面研究,利用了2005-2020年国家健康和营养检查调查 (NHANES) 的23,154名参与者的数据.
- 使用患者健康问卷-9评估抑郁症,通过BMI和腰围测量肥胖症.
- 使用了后勤回归,受限立方线 (RCS) 和调解效应分析.
主要成果:
- 在较高的抑郁水平和增加的湿OAB风险 (ORs从2.34到3.14) 之间发现了显著的积极关联.
- 一般和腹部肥胖都与增加的抑郁症和湿OAB风险有显著联系.
- 肥胖部分介导了抑郁症和湿OAB之间的关联,一般肥胖占5.16%和腹部肥胖占间接影响的4.25%.
结论:
- 较高的抑郁症与较高的湿OAB风险有关,特别是在肥胖个体中.
- 一般和腹部肥胖症在从抑郁症到湿OAB的途径中起着重要的部分调解作用.
- 综合心理健康干预和体重管理策略对于湿OAB患者至关重要.
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