在早产婴儿中,脂肪质量的短期和长期增长和发展
Shipra Jain1, Belal N Alshaikh2, Seham Elmrayed3
1The Perinatal Institute, Cincinnati Children's Hospital Medical Center, 3333 Burnett Avenue, Cincinnati 45229, Ohio, USA; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
Seminars in fetal & neonatal medicine
|May 15, 2025
概括
促进早产婴儿的快速早期生长对于发育至关重要,并且不会对长期代谢健康产生负面影响. 响应式养支持最佳的生长和神经发育,而不会影响未来的福祉.
科学领域:
- 新生儿营养新生儿营养
- 儿科生长和发育的发展.
- 代谢健康结果的结果
背景情况:
- 过早生育的婴儿最初的生长速度很快,但容易出现生长迟缓的情况.
- 人们担心,在追赶成长期间,早产婴儿的脂肪增加.
- 与早产婴儿早期快速生长相关的长期代谢风险需要调查.
研究的目的:
- 评估早产婴儿的长期代谢健康结果,这些婴儿在出生后快速增长.
- 为了确定早产婴儿的早期生长促进是否会影响以后的脂肪和代谢健康.
- 评估养方法对早产婴儿生长和神经发育的影响.
主要方法:
- 系统性审查分析了超过2万个人的数据.
- 在早产和早产婴儿之间比较身体组成,BMI和代谢标志物.
- 长度评估从婴儿期到成年期的生长轨迹和肥胖度.
主要成果:
- 过早出生婴儿的较高体脂在经期校正的年龄下降3个月的校正年龄.
- 对于怀孕年龄来说小的早产婴儿没有增加儿童脂肪;有些婴儿的BMI较低.
- 在早产儿中促进早期生长不会影响长期的代谢结果或神经发育.
结论:
- 促进早产儿的早期生长是安全的,对神经发育有好处.
- 灵敏的养,以婴儿线索为指导,支持健康的生长和长期健康.
- 优化早产婴儿的生长并不需要立即发展和未来的代谢健康之间的权衡.
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