相关实验视频

Updated: May 17, 2025

Author Spotlight: A Computational Approach to Decipher Amino Acid Preferences in Multispecific Protein-Protein Interactions
06:50

Author Spotlight: A Computational Approach to Decipher Amino Acid Preferences in Multispecific Protein-Protein Interactions

Published on: January 26, 2024

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3D-ΔΔG:基于蛋白质3D结构的突变后蛋白质-蛋白质结合亲和力变化的双通道预测模型

Yuxiang Wang1, Yibo Zhu1, Xiumin Shi1

  • 1School of Information and Electronics, Beijing Institute of Technology, Beijing, China.

Proteins
|May 15, 2025
PubMed
概括

预测蛋白质-蛋白质结合亲和力 (ΔΔG) 的变化对于了解疾病至关重要. 一个新的深度学习模型,3D-ΔΔG,使用序列和结构数据准确地预测单个和多个突变的ΔΔG.

关键词:
深度学习是一种深度学习.预先训练的蛋白质语言模型.蛋白质蛋白质结合亲和力 亲和力蛋白质蛋白质相互作用的 ΔΔGΔG 的时间.

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