老年患者手术前并发症和术后痴呆症组合之间的关联:一项匹配的队列研究
Ao Li1, Yuxiang Song1, Wenzhu Shi1
1Department of Anesthesiology, The First Medical Center of Chinese PLA General Hospital, Beijing, China.
BMC anesthesiology
|May 15, 2025
概括
手术前的并发症,如高血压,增加了老年手术患者手术后妄想症 (POD) 的风险. 这些条件的组合,特别是高血压,进一步提高POD风险.
科学领域:
- 老年医学 老年医学
- 外科手术的结果
- 流行病学 流行病学
背景情况:
- 手术后妄 (POD) 是老年手术患者的一个重大问题.
- 确定POD的术前风险因素对于患者管理至关重要.
研究的目的:
- 调查术前并发症与患术后妄想症的风险之间的关联.
- 为了确定合并疾病的组合是否会增加POD的风险.
主要方法:
- 倾向性得分匹配的队列研究使用了2014-2019年的回顾性数据.
- 对接受手术的老年患者的分析,对单变风险因素进行逻辑回归.
- 在患有POD和没有POD的患者中比较并发症组合.
主要成果:
- 在POD患者中,八种术前并发症 (高血压,糖尿病,心房动,脑血管疾病,帕金森病,,抑郁症,慢性肺炎) 较为频繁.
- 患有POD的患者更有可能患有高血压和脑血管疾病的组合,或高血压和COPD.
- 共有1034名患者患有POD,与3102名对照组相匹配.
结论:
- 多重手术前并发症与老年手术患者的POD风险更高有关.
- 同时出现的并发症,特别是涉及高血压的并发症,显著增加POD的可能性.
- 高血压成为POD发展中的中心并发症.
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