Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Evolutionary Relationships through Genome Comparisons02:54

Evolutionary Relationships through Genome Comparisons

5.6K
Genome comparison is one of the excellent ways to interpret the evolutionary relationships between organisms. The basic principle of genome comparison is that if two species share a common feature, it is likely encoded by the DNA sequence conserved between both species. The advent of genome sequencing technologies in the late 20th century enabled scientists to understand the concept of conservation of domains between species and helped them to deduce evolutionary relationships across diverse...
5.6K
Gene Evolution - Fast or Slow?02:05

Gene Evolution - Fast or Slow?

7.0K
The genomes of eukaryotes are punctuated by long stretches of sequence which do not code for proteins or RNAs. Although some of these regions do contain crucial regulatory sequences, the vast majority of this DNA serves no known function. Typically, these regions of the genome are the ones in which the fastest change, in evolutionary terms, is observed, because there is typically little to no selection pressure acting on these regions to preserve their sequences.
In contrast, regions which code...
7.0K
Genome Annotation and Assembly03:36

Genome Annotation and Assembly

18.7K
The genome refers to all of the genetic material in an organism. It can range from a few million base pairs in microbial cells to several billion base pairs in many eukaryotic organisms. Genome assembly refers to the process of taking the DNA sequencing data and putting it all back together in a correct order to create a close representation of the original genome. This is followed by the identification of functional elements on the newly assembled genome, a process called genome annotation.
18.7K
Phylogenetic Trees03:21

Phylogenetic Trees

44.9K
Phylogenetic trees come in many forms. It matters in which sequence the organisms are arranged from the bottom to the top of the tree, but the branches can rotate at their nodes without altering the information. The lines connecting individual nodes can be straight, angled, or even curved.
44.9K
Karyotyping01:17

Karyotyping

55.6K
Overview
55.6K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Sequence Flow: interactive web application for visualizing partial order alignments.

BMC genomics·2024
Same author

Linearization of genome sequence graphs revisited.

iScience·2021
Same author

Getting insight into the pan-genome structure with PangTree.

BMC genomics·2020
Same author

qDSB-Seq is a general method for genome-wide quantification of DNA double-strand breaks using sequencing.

Nature communications·2019
Same author

Comprehensive Mapping of Histone Modifications at DNA Double-Strand Breaks Deciphers Repair Pathway Chromatin Signatures.

Molecular cell·2018
Same author

Defective XRN3-mediated transcription termination in Arabidopsis affects the expression of protein-coding genes.

The Plant journal : for cell and molecular biology·2018
Same journal

A k-mer-based estimator of the substitution rate between repetitive sequences.

Algorithms for molecular biology : AMB·2026
Same journal

Haplotype-aware long-read error correction.

Algorithms for molecular biology : AMB·2026
Same journal

Extension of partial atom-to-atom maps: uniqueness and algorithms.

Algorithms for molecular biology : AMB·2026
Same journal

Lossless pangenome indexing using tag arrays.

Algorithms for molecular biology : AMB·2026
Same journal

Dolphyin: a combinatorial algorithm for identifying 1-Dollo phylogenies in cancer.

Algorithms for molecular biology : AMB·2026
Same journal

Probing transcription factor subsets in gene regulatory networks.

Algorithms for molecular biology : AMB·2026
查看所有相关文章

相关实验视频

Updated: May 17, 2025

Heuristic Mining of Hierarchical Genotypes and Accessory Genome Loci in Bacterial Populations
08:03

Heuristic Mining of Hierarchical Genotypes and Accessory Genome Loci in Bacterial Populations

Published on: December 7, 2021

2.0K

阿尔法Pang:为 pangenome 图形构建的无对齐算法.

Adam Cicherski1, Anna Lisiecka2, Norbert Dojer3

  • 1Institute of Informatics, University of Warsaw, Banacha 2, 02-097, Warsaw, Poland. a.cicherski2@uw.edu.pl.

Algorithms for molecular biology : AMB
|May 15, 2025
PubMed
概括
此摘要是机器生成的。

阿尔法潘格 (AlfaPang) 是一种用于构建泛基因组图的新算法,对基因组学至关重要. 这种无对齐的方法使用的计算资源比大型基因组集合的现有工具要少.

关键词:
基因组对齐是如何实现的潘格诺姆是一个名字.人口基因组学是人口的基因组学.变化图的变化图表

更多相关视频

A Novel Bayesian Change-point Algorithm for Genome-wide Analysis of Diverse ChIPseq Data Types
12:39

A Novel Bayesian Change-point Algorithm for Genome-wide Analysis of Diverse ChIPseq Data Types

Published on: December 10, 2012

11.3K
Novel Sequence Discovery by Subtractive Genomics
09:40

Novel Sequence Discovery by Subtractive Genomics

Published on: January 25, 2019

8.5K

相关实验视频

Last Updated: May 17, 2025

Heuristic Mining of Hierarchical Genotypes and Accessory Genome Loci in Bacterial Populations
08:03

Heuristic Mining of Hierarchical Genotypes and Accessory Genome Loci in Bacterial Populations

Published on: December 7, 2021

2.0K
A Novel Bayesian Change-point Algorithm for Genome-wide Analysis of Diverse ChIPseq Data Types
12:39

A Novel Bayesian Change-point Algorithm for Genome-wide Analysis of Diverse ChIPseq Data Types

Published on: December 10, 2012

11.3K
Novel Sequence Discovery by Subtractive Genomics
09:40

Novel Sequence Discovery by Subtractive Genomics

Published on: January 25, 2019

8.5K

科学领域:

  • 基因组学就是基因组学.
  • 生物信息学是一种生物信息学.

背景情况:

  • 庞基因组图构造对于分析大型基因组集合至关重要.
  • 当前的方法往往需要大量的计算资源,限制了可扩展性.

研究的目的:

  • 为了介绍AlfaPang,一个新的算法,用于高效的 pangenome 图形构建.
  • 提出一种无对齐的方法,减少计算需求.

主要方法:

  • 开发了AlphaPang,一种新的万科组图构建算法.
  • 用了一种新的无对齐策略来构建图形.

主要成果:

  • 阿尔法潘格高效地构建了潘格诺姆图.
  • 与最先进的工具相比,该算法需要的计算资源要少得多.
  • 已证明适用于大型基因组收集.

结论:

  • 阿尔法Pang提供了一个高效和节约资源的替代方案,用于 pangenome 图形构建.
  • 无对齐方法提高了对广泛的基因组数据集进行泛基因组分析的可行性.