在二次心血管预防中测量对他类药物的坚持的方法和有效性指标:系统性审查
Adriana López-Pineda1,2,3, María Martinez-Muñoz1, Rauf Nouni-García4,5,6
1Department of Clinical Medicine, University of Miguel Hernandez Elche, Sant Joan d'Alacant, Comunidad Valenciana, Spain.
Systematic reviews
|May 15, 2025
概括
在心血管患者中测量他类药物的坚持通常使用未经验证的间接方法,如处方补充. 需要新的验证工具来准确评估二次预防中的药物坚持.
科学领域:
- 心血管医学 心血管医学
- 药理学 药理学是指药理学的学科.
- 医疗保健服务研究 医疗服务研究
背景情况:
- 坚持使用他类药物治疗对于预防复发性心血管事件至关重要.
- 准确测量药物坚持对于临床实践至关重要.
- 本综述侧重于二次心血管预防中的他类药物的坚持和持续性.
研究的目的:
- 确定用于测量他类药物的坚持和持续性的方法.
- 评估这些测量方法的有效性指标.
- 为临床实践提供有关合适的依从性评估工具的信息.
主要方法:
- 对测量他类药物的坚持/持久性的研究进行系统审查.
- 在Medline,Embase和Scopus数据库中搜索到2025年2月.
- 使用COSMIN工具评估研究有效性.
主要成果:
- 处方补充记录 (55项研究) 和自我报告 (20项研究) 是最常见的坚持.
- 持续性主要通过处方补充记录 (9项研究) 来衡量.
- 很少有研究报告了有效性指标;没有人对他类药物的间接方法进行了验证.
结论:
- 间接方法 (处方记录,自我报告) 主导着他类药物坚持度的测量.
- 目前的间接方法缺乏对他类药物坚持的验证.
- 需要有效的工具,考虑到性别,以准确评估他类药物坚持.
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