对于无家可归的人来说,结合戒烟和戒酒治疗:一个随机试验
Olanrewaju Onigbogi1, Rebekah Pratt2, Xianghua Luo3
1Department of Family Medicine, Indiana University, 980 Indiana Avenue, Indianapolis, IN.
概括
对戒烟和戒酒的生物行为干预措施并没有显著改善无家可归成年人的结果. 对于有效的干预措施,需要进行持续的研究,以解决该人口中同时出现的物质使用问题.
科学领域:
- 公共卫生 公共卫生
- 成 药物 药物 药物 药物
- 行为科学 行为科学
背景情况:
- 80%的美国无家可归的成年人吸烟可燃性香烟.
- "戒烟的力量2" (PTQ2) 试验研究了戒烟和戒酒的联合干预措施.
- 经历无家可归的成年人面临着与同时出现的物质使用的重大挑战.
研究的目的:
- 与常规护理 (UC) 相比,测试强度吸烟加酒精 (IS+A) 干预措施的有效性.
- 评估IS + A对干预后26周禁烟的影响.
- 评估IS+A对干预后26周酒精戒断的影响.
主要方法:
- 一项随机临床试验 (PTQ2) 涉及无家可归者庇护所的344名成年人.
- 参与者被随机分配到IS + A (认知行为疗法 + 尼古丁替代疗法) 或UC (教育会议 + 尼古丁替代疗法).
- 主要结局:经生物化学验证的7天点流行性禁烟26周.
- 二次结局:自报30天的酒精戒断26周.
主要成果:
- 在26周的IS+A (16.6%) 和UC (12.8%) 之间,吸烟戒断没有显著差异 (P=0.47).
- 在26周的IS+A (91.1%) 和UC (90.2%) 之间,酒精戒断没有显著差异 (P=0.75).
- 趋势有利于IS+A组戒烟,尽管在统计学上并不显著.
结论:
- 通过IS+A干预,戒烟和戒酒的结果并没有比通常的治疗更好.
- 该研究强调了无家可归人口同时戒烟和戒酒干预措施的复杂性.
- 对生物行为干预措施的进一步研究对于解决无家可归的成年人同时出现的物质使用至关重要.
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