风湿性关节炎在中国城市的流行和发病率:一项基于全国人口的研究
Mengzhuo Cao1,2,3,4, Chaiquan Li5, Mucong Li1,2,3,4
1Department of Rheumatology and Clinical Immunology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China.
International journal of rheumatic diseases
|May 16, 2025
概括
中国的风湿性关节炎 (RA) 患病率和发病率高且不断增加,特别是在老年女性中. 该研究强调了严重的经济负担,人均年平均成本约为908美元.
科学领域:
- 流行病学 流行病学
- 公共卫生 公共卫生
- 类风湿病学 类风湿病学
背景情况:
- 风湿性关节炎 (RA) 是一个重大的全球健康挑战.
- 在中国缺乏关于RA的流行,发病率和经济影响的全面全国数据.
研究的目的:
- 通过大规模人口数据,估计中国RA的流行率和发病率.
- 分析RA率的人口和区域变化.
- 为了确定与RA相关的经济负担.
主要方法:
- 一项以人口为基础的研究利用了中国23个省份 (2013-2017) 的3.8亿居民的医疗保险索赔.
- 两阶段的波桑回归模型被用来估计年龄和性别标准化的流行率和发病率.
- 计算了年度成本和医院访问频率.
主要成果:
- 2017年,标准化RA患病率为每10万人334.35,女性患病率更高 (443.97/100,000),平均年增长率为21.79%.
- 2017年的发病率为每10万人/年128.71,在65-74岁年龄组达到顶峰.
- 在中国南部,流行率和发病率较低,人均年平均成本为907.78.8美元.
结论:
- 在中国,高且不断增加的RA患病率,发病率和医疗费用,对社会造成了巨大的负担.
- 观察到的RA患病率的区域差异需要进一步调查潜在原因.
- 这些发现强调了需要针对性公共卫生战略和资源配置,以对抗中国的RA管理.
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