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Updated: May 17, 2025

Anionic Polymerization of an Amphiphilic Copolymer for Preparation of Block Copolymer Micelles Stabilized by π-π Stacking Interactions
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在OEGylated超分子聚合物中平衡化学和超分子稳定性

Weijie Zhang1, Feihu Wang1, Han Wang1

  • 1Department of Chemical and Biomolecular Engineering and Institute for NanoBioTechnology, The Johns Hopkins University, 3400 North Charles Street, Baltimore, Maryland 21218, United States.

Journal of the American Chemical Society
|May 16, 2025
PubMed
概括

甲基乙烯糖醇 (OEG) 修改了坎普托丁 (CPT) 产生了具有增强抗癌功能的自我组装超分子聚合物 (SP). 在结肠癌模型中,从具有特定链接剂的SP中释放CPT的速度提高了瘤抑制和存活率.

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