与酒精性酸性相关的急性食道坏死病例报告
Laurin Egli1, Alexa Hollinger1,2, Anne Leuppi-Taegtmeyer2,3
1Intensive Care Unit, University Hospital Basel, Basel, Switzerland.
Journal of intensive care medicine
|May 16, 2025
概括
急性食道死 (AEN),或"黑食道",是一种罕见的疾病,导致上部胃肠道出血. 这一案例突显了一个年轻人的AEN与酒精酸性脂肪酸症,饥饿和药物改变有关.
科学领域:
- 胃肠病学 胃肠病学
- 内部医学 内部医学
- 毒理学 毒理学 毒理学
背景情况:
- 急性食道死 (AEN),也被称为"黑食道"或古尔维特综合征,是一种罕见的疾病.
- 它是由食道缺血,胃液腐蚀和粘膜防御能力降低造成的.
- 临床表现包括上部胃肠道出血,腹痛,恶心,吐,消化不良和发烧.
研究的目的:
- 在年轻人中报告罕见的AEN病例.
- 探索潜在的促成因素,包括酒精性酸性脂肪酸症,长时间的饥饿和药物变化.
主要方法:
- 用于诊断的食道胃肠透镜 (EGD).
- 审查患者的病史,包括物质使用和药物摄入.
主要成果:
- 关于EGD的核心发现是食道周围的黑色变色,主要是在远端段.
- 该患者出现了与AEN一致的症状,并且有过度饮酒,长时间饥饿以及增加了venlafaxine和quetiapine的摄入.
- 这种情况与酒精性酸性脂肪酸症有关.
结论:
- 通常在伴随疾病的老年男性中观察到的AEN,可以在年轻人中发生.
- 酒精性酸性脂肪酸,饥饿和某些药物可能是AEN的诱发因素.
- 这种病例扩大了已知的临床谱和急性食道死的潜在触发因素.
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