日本儿科炎性肠病管理的发展趋势:十年的全国数据
Miki Urushiyama1, Kunio Tarasawa2, Rintaro Moroi1
1Division of Gastroenterology Tohoku University Hospital Sendai Japan.
概括
日本的儿科炎性肠病 (IBD) 管理显示出一种趋势,即采用少入侵的治疗方法. 生物药物和囊内镜的使用增加,而儿童克罗恩病和性结肠炎患者的手术和其他侵入性方法减少.
科学领域:
- 胃肠病学 胃肠病学
- 儿科医学 儿科医学
- 医学趋势分析 医学趋势分析
背景情况:
- 儿童炎症性肠病 (IBD),包括克罗恩病 (CD) 和性结肠炎 (UC),需要不断发展的管理策略.
- 了解治疗趋势对于优化年轻患者的护理至关重要.
研究的目的:
- 调查十年 (2012-2022) 期间日本儿科IBD的管理趋势.
- 分析利用各种治疗方式的转变.
主要方法:
- 对日本全国数据库 (2012-2022) 的回顾性分析.
- 包括15岁或更年轻的患者,被诊断患有CD或UC.
- 通过使用统计趋势测试,检查生物药物,囊内镜,全肠直肠营养 (TPN),元素饮食,手术以及颗粒细胞和单细胞非 (GMA) 的趋势.
主要成果:
- 儿童CD (46.0%至53.6%) 和UC (15.0%至33.0%) 的生物使用显著增加.
- 对CD的囊内镜显著增加 (6.6%至16.7%) 和TPN使用减少 (8.4%至3.0%).
- 降低了UC的手术率 (3.7%至1.7%) 和UC的GMA显著减少 (12.1%至2.7%).
结论:
- 日本的儿科IBD管理已经转向增加生物药物和囊内镜的使用.
- 有一个明显的趋势,远离更多的侵入性治疗,如手术和GMA.
- 这些发现表明,儿童IBD的治疗方法越来越少入侵,越来越有针对性.
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