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早期暴露于细颗粒物和精细运动功能,注意力功能和工作记忆在西班牙学龄儿童中

Kristina W Whitworth^1,2, Aitana Lertxundi^3,4,5, Mingze Yuan²

¹Department of Medicine, Section of Epidemiology and Population Sciences, Baylor College of Medicine, Houston, Texas.

Environmental epidemiology (Philadelphia, Pa.)

|May 16, 2025

概括

这项研究发现了有限的证据,将细颗粒物 (PM2.5) 暴露与儿童的神经心理功能联系起来. 早期生活中,PM2.5与运动技能,注意力或工作记忆没有明确的关联.

科学领域:

环境健康环境健康
神经科学是一个神经科学.
儿科儿科儿科

背景情况:

儿童暴露于细颗粒物 (PM2.5) 与神经心理发展有着争论的关联.
目前关于PM2.5对儿童认知功能的影响的证据不一致.

研究的目的:

调查早期生活中PM2.5暴露与儿童神经心理结果之间的关系.
评估PM2.5在幼儿时期对精细运动功能,注意力和工作记忆的影响.

主要方法:

利用了西班牙INfancia y Medio Ambiente项目 (2003-2008) 的数据.
使用基于住宅历史的时空空间土地使用随机森林模型评估PM2.5暴露.
对6岁左右的儿童进行了神经心理测试 (指纹敲击,ANTT,n-back).
采用一般线性模型和分布式滞后非线性模型来分析关联并确定敏感的暴露期.

主要成果:

产前PM2.5暴露在ANT上显示了与注意力指标 (HRT) 的不准确关联.
产后的PM2.5暴露与对n-back任务的注意力有关,尽管具有广泛可信的间隔.
对于精细运动和注意力功能,在产后阶段确定了敏感的暴露期.

结论:

有限的证据支持PM2.5暴露与学龄儿童的精细运动,注意力或工作记忆之间的联系.
这些发现表明,早期生活中的PM2.5暴露可能不会显著影响这些特定的神经心理领域.

关键词:

空气污染大气污染注意力网络测试试验认知能力认知能力执行职能执行职能执行职能精细运动功能精细运动功能用手指点击测试的测试对于PM2.5来说,这是一个很好的例子.易受影响的窗户在 n-back 任务任务中.

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