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扫描仪生成的原生T1映射:在冠心病中评估心肌纤维化的一个新方法

Li Kong¹, Xiaohong Tian², Bing Ji²

¹Department of Ultrasound, Children's Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Engineering Research Center of Stem Cell Therapy, Chongqing, China.

Frontiers in cardiovascular medicine

|May 16, 2025

概括

来自图像存档和通信系统 (PACS) 的原生T1映射值可以评估冠心病 (CHD) 中的扩散性心肌纤维化. 这种非侵入性工具显示出有希望的准确性,用于评估心血管疾病患者的纤维化.

科学领域:

心血管成像 - 心血管成像
医学物理医学物理
放射学放射学是一门学科.

背景情况:

冠心病 (CHD) 可能导致扩散性心肌纤维化.
非侵入性评估心肌纤维化对于患者管理至关重要.
原生纵向放松时间 (T1) 映射是一种潜在的成像生物标志物.

研究的目的:

评估使用来自图像存档和通信系统 (PACS) 的原生T1映射值来评估心脏病患者的扩散性肌肉纤维化.
为了将本源T1值与心脏病患者的细胞外体积 (ECV) 相对应.

主要方法:

追溯招募患有心血管疾病的患者和健康对照组.
心脏磁共振 (CMR) 成像与晚期加多增强 (LGE) 序列.
原生T1映射和ECV测量.
皮尔森相关系数用于评估T1和ECV相关性.

主要成果:

与对照组相比,CHD组的原生T1和ECV值显著增加 (P <0.05).
在原生T1和ECV值之间发现了正相关性 (r = 0.711,P < 0.01).
原生T1映射显示,用于诊断纤维化,接收器操作特征曲线 (AUC) 下的面积为0.763,最佳值为1,275.50毫秒 (灵敏度93.3%,特异性63.3%).

结论:

扫描仪生成的本地T1映射对于评估心脏病中扩散性心肌纤维化是准确的.
原生T1映射具有作为CHD纤维化评估的非侵入性工具的潜力.
来自PACS的原生T1值为纤维化评估提供了一种可行的方法.

关键词:

在CMR中,CMR是CMR.在ECV中,它是ECV.PACS PACS 是一个小组.冠心病是一种冠心病.血中位数是什么意思血中位数是什么意思侵袭性冠状动脉血管学侵袭性冠状动脉血管学

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