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Updated: Jul 13, 2026

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使用聚乙烯胺转移未经修改的寡度氧核酸减少B型肝炎表面抗原的水平

Junyu Lin1, Jing Li2

  • 1Research Center for Basic Medical Science, Qilu Hospital of Shandong University, Jinan, Shandong, China.

Frontiers in microbiology
|May 16, 2025
PubMed
概括

聚乙烯胺 (PEI) 和寡核酸复合物有效地降低了B型肝炎表面抗原 (HBsAg) 在细胞培养和小鼠中的分泌. 这表明PEI/寡核酸转感染是开发新的抗乙型肝炎病毒 (HBV) 治疗的有前途的战略.

关键词:
在HBsAg的分泌中.对抗HBV的治疗方法.乙型肝炎病毒感染 乙型肝炎病毒感染非病毒基因载体的非病毒基因载体提供未经修改的寡核酸.

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