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化学抗原受体-巨细胞:新兴的下一代细胞疗法用于脑癌

Myrthe J A Koppers1, Matthijs Monnikhof1, Jan Meeldijk2,1

  • 1Department of Pathology, University Medical Center Utrecht, Utrecht, The Netherlands.

Neuro-oncology advances
|May 16, 2025
PubMed
概括

化学抗原受体 (CAR) -T疗法对大脑瘤有希望,但面临挑战. 汽车巨细胞 (CAR-MACs) 提供了一种新的方法,证明了增强的瘤透和脑癌免疫疗法的有效性.

关键词:
它们是CAR巨细胞.采用细胞疗法采用细胞疗法大脑瘤是个大脑瘤仿制性抗原受体的仿制性抗原受体瘤微环境是一个微环境.

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Tumor Immunotherapy

Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
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