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在IBD患者中脊椎关节炎的特征:患病率,转诊趋势和临床影响. 一个基于问卷的研究
Nina Pettersson1, Fredrik Kragbjerg1, Arvid Hamrin2
1Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden.
Scandinavian journal of gastroenterology
|May 16, 2025
概括
许多炎症性肠病 (IBD) 患者表现出脊髓关节炎 (SpA) 的特征,但很大一部分仍未被诊断并未转诊给类风湿病学家,这凸显了改善护理协调的需要.
科学领域:
- 胃肠道学和风湿病学
- 临床免疫学临床免疫学
- 流行病学 流行病学
背景情况:
- 炎症性肠病 (IBD) 通常与肠外表现有关,包括脊椎关节炎 (SpA).
- 在IBD患者中早期发现和治疗SPA对于改善患者的治疗结果至关重要.
- 在IBD患者中,对SPA的诊断和转诊途径存在公认的差距.
研究的目的:
- 在一组炎症性肠病 (IBD) 患者中调查脊椎关节炎 (SpA) 特征的患病率.
- 为了确定具有SpA特征的IBD患者转诊类风湿病学家的比率.
- 确定与IBD中疑似轴向和外周SPA相关的因素.
主要方法:
- 根据适应的ASAS和ESSG标准,对瑞典的2087名IBD患者进行了评估人口统计,药物和SPA特征的问卷调查.
- 1032名IBD患者有反应,那些符合自我报告的适应标准的人被归类为可疑的SPA.
- 使用后勤回归分析来确定与可疑的SpA相关的因素.
主要成果:
- 59.1%的IBD受访者符合基于问卷的调整后的SPA标准.
- 在怀疑SPA的患者中,转诊风湿病学家的比例在24.3%至44.0%之间.
- 疑似SPA患者使用免疫调节剂,生物制剂和类固醇的比例更高,活性结肠炎的发病率更高.
- 与轴性SPA相关的因素包括年龄,吸烟,牛皮,前膜炎和高P-SCCAI得分;女性性别和高BMI与外围SPA相关.
结论:
- 在IBD患者群体中,自报告的SpA特征的显著流行存在.
- 许多具有SpA特征的IBD患者没有被转诊给风湿病学家,这表明潜在的诊断和管理差距.
- 提高胃肠科医生和风湿病学家之间的意识和跨学科合作对于优化IBD患者的SPA管理至关重要.
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