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Updated: May 17, 2025

Using Caenorhabditis elegans as a Model System to Study Protein Homeostasis in a Multicellular Organism
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Using Caenorhabditis elegans as a Model System to Study Protein Homeostasis in a Multicellular Organism

Published on: December 18, 2013

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蛋白质稳定网络的特定分支调节与错误翻译相关的毒性

Donovan W McDonald1, Rebecca N Dib2, Christopher De Luca2

  • 1Department of Biology, The University of Western Ontario, London, ONN6A 3K7, Canada.

Nucleic acids research
|May 16, 2025
PubMed
概括

错误翻译转移RNA (tRNA) 变体对细胞健康有不同的影响. 特定的tRNA错误通过不同的机制破坏蛋白质折叠和降解途径,影响蛋白质静止.

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