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Updated: May 21, 2025

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转录因子与NIPBL/MAU2形成三元复合体,以在增强剂上定位凝聚蛋白

Gregory Fettweis1, Kaustubh Wagh2, Diana A Stavreva2

  • 1Laboratory of Gene Expression and Cancer, GIGA-Molecular & Computational Biology, University of Liège, 4000 Liège, Belgium.

Nucleic acids research
|May 16, 2025
PubMed
概括

凝聚素加载器NIPBL (NIPBL/MAU2) 对增强剂的局部化是由转录因子相互作用介导的. 在NIPBL中的特定LxxLL基因结合MAU2和类固醇受体,如葡萄糖皮质体受体 (GR),影响基因调节.

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