多发性硬化症妇女的乳腺癌查:一种混合方法研究
Pierret Chloe1, Philippe Lou1, Leray Emmanuelle1
1Rennes University, EHESP, CNRS, Inserm, ARENES UMR 6051, RSMS U 1309, Rennes, France.
European journal of neurology
|May 16, 2025
概括
与一般人群相比,患有多发性硬化症 (MS) 的女性的乳腺癌查 (BCS) 较少. 改善这些女性的BCS,特别是那些不接受疾病修饰疗法 (DMT) 的女性,至关重要.
科学领域:
- 在瘤学瘤学.
- 神经学 神经学
- 公共卫生 公共卫生
背景情况:
- 关于患有多发性硬化症 (WwMS) 的女性乳腺癌查 (BCS) 实践的数据有限.
- 了解WwMS中的BCS率和相关因素对于有针对性的干预措施至关重要.
研究的目的:
- 为了比较WwMS和普通人群之间的BCS率.
- 确定影响BCS在WwMS中的遵守的障碍和促进者.
主要方法:
- 2012-2020年的法国队列研究比较了47,166个WwMS与184,124个对照组.
- 根据人口统计,社会经济地位和疾病修饰疗法 (DMT) 使用情况,分析了乳房扫描率.
- 通过对20个WwMS进行半结构面试,收集了定性数据.
主要成果:
- 与对照组相比,WwMS的BCS率较低 (69.9%vs. 76.7%) 和两年一次的乳房造影率较低 (0.55vs. 0.63).
- 较低的发病率与社会经济地位,较长的MS持续时间和住院住院有关;使用DMT与较高的发病率有关.
- 障碍物包括身体残疾和感知到的医疗;促进者是可访问的护理和常规感知.
结论:
- 在WWMS中BCS是低于最佳的,特别是对于那些没有接受DMT的人来说.
- 需要采取干预措施来提高查遵守率,并解决已识别的障碍.
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