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在性别肯定激素治疗期间肌肉强度的变化和身体活动:系统性审查
Mathilde Kamp Nørlund1,2, Louise Lehmann Christensen2, Marianne Skovsager Andersen2
1Faculty of Health Sciences, Clinical Institute, University of Southern Denmark, Odense, Denmark.
Andrology
|May 16, 2025
概括
性别肯定激素治疗影响肌肉力量,男性化疗法增加肌肉力量,女性化疗法减少肌肉力量. 身体活动水平保持不变,凸显了对跨性别个体进行进一步研究和参与运动的需要.
科学领域:
- 内分泌学和新陈代谢学
- 运动医学和运动科学 运动医学和运动科学
- 跨性别者健康 跨性别者健康
背景情况:
- 更高的肌肉力量与更好的整体健康和降低死亡率有关.
- 在性别肯定激素治疗 (GAHT) 期间肌肉强度的变化可能会受到治疗类型,年龄,持续时间和身体活动的影响.
研究的目的:
- 系统地审查现有文献,以了解跨性别个体经历GAHT时肌肉力量的变化.
主要方法:
- 根据PICOS标准进行了一项文献综述.
- 包括的研究集中在接受GAHT的跨性别个人 (≥18岁) 上,与未接受GAHT的个人或 cisgender对照相比.
- 评估结果是肌肉力量和体力活动;研究设计包括前性队列和横截面研究.
主要成果:
- 分析了15项涉及1206名跨性别者的研究 (722名跨性别者,484名跨性别者).
- 在4/6的研究中,男性化GAHT增加了肌肉力量,而女性化GAHT在3/6的研究中降低了肌肉力量.
- 强度变化在GAHT的第一年是最显著的;体力活动一般保持不变.
结论:
- 雄性化的GAHT似乎增强了肌肉力量,而女性化的GAHT可能会减少它.
- 身体活动水平在GAHT期间没有显著变化.
- 鉴于包含的研究中偏见的风险中等至高,进一步的研究是必不可少的,强调体育活动参与跨性别护理的重要性.
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