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Updated: May 17, 2025

DNAzyme-dependent Analysis of rRNA 2’-O-Methylation
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DNAzyme-dependent Analysis of rRNA 2’-O-Methylation

Published on: September 16, 2019

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16S rRNA 的 RsmG 甲基化会影响核糖体蛋白 uS12 的功能

Trevor W Bell1, Rowan M Turner1, Amanda M Merryman1,2

  • 1Division of Biology and Biomedical Systems, School of Science and Engineering, University of Missouri-Kansas City, Rm 306 Spencer Hall5007 Rockhill Rd., Kansas City, MO, 64110, USA.

Archives of microbiology
|May 16, 2025
PubMed
概括

在大肠杆菌中禁用RsmG甲基转移酶可能会导致高水平的 estreptomycin 耐药性,特别是当与核糖体蛋白 uS12 的特定突变相结合时. 这一发现揭示了细菌对 estreptomycin 耐药性的新途径.

关键词:
里博索姆RNA甲基酶的发生核糖体蛋白 uS12 的蛋白质在RsmG中,我们可以使用RsmG.链杆菌素耐药性 链杆菌素耐药性

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