使用CMR二维相对比和四维流在二次中枢排泄中的流量量化的可复制性和可靠性
Yasaman Safarkhanlo1,2,3, Martina Boscolo Berto1, Giancarlo Spano1
1Department of Cardiology, Inselspital, University Hospital Bern, Bern, CH-3010, Switzerland.
The international journal of cardiovascular imaging
|May 16, 2025
概括
2D相对比标准方法提供了使用心脏磁共振成像 (CMR) 的最可重现的对心心回 (MVR) 的量化. 虽然4D流方法显示了高的读器内部协议,但读器之间的可复制性更为可变.
科学领域:
- 心血管成像 - 心血管成像
- 医学物理 医学物理
- 定量分析 定量分析
背景情况:
- 准确量化关反 (MVR) 对于临床决策至关重要.
- 心脏磁共振成像 (CMR) 为MVR量化提供了各种方法,但它们的可重现性尚未得到充分证实.
- 评估不同CMR技术的可靠性对于其临床采用至关重要.
研究的目的:
- 评估不同2D相对比 (PC) 和4D流CMR方法的MVR量化的读者间和读者内可重现性.
- 为了比较七种不同的MVR量化技术在患有二次MVR的患者中的可靠性.
主要方法:
- 评估了七种MVR量化方法:2D-PC标准,2D-PC中枢大动脉,2D-PC直接,4D流量标准,4D流量中枢大动脉,4D流量直接和体积方法.
- 可复制性是通过两个独立的读者使用类内相关系数 (ICC) 来评估的.
- 该研究包括32名二次MVR患者,对26名2D-PC和15名4D流方法进行了分析.
主要成果:
- 2D-PC标准方法显示出最高的可重现性,具有良好的读者间 (ICC=0.85) 和读者内部 (ICC=0.87) 协议.
- 4D流标准方法显示出良好的读器内部一致性 (ICC=0.97),但只有中等的读器间可重复性 (ICC=0.52).
- 体积测量方法具有良好的读者内部一致性 (ICC=0.81),但在读者之间具有中度的可重复性 (ICC=0.71).
结论:
- 2D-PC标准方法是MVR量化在二次MVR患者中最可复制的技术.
- 4D流方法在读器内具有很高的可靠性,但需要标准化的协议来提高读器间的一致性.
- 建议对更大的队列和临床结果相关性进行进一步的研究,以优化这些CMR量化技术.
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