协议: 体重调整后有效体积为0.5%的罗皮瓦卡因,用于经过关节镜肩部手术的结合性 costoclavicular 支臂块 - 椎块: 一个剂量确定研究协议
Jianlin Wang1, Liyong Yuan1, Zhong Mei2
1Department of Anesthesiology, Ningbo No.6 Hospital, Ningbo University School of Medicine, Ningbo, Zhejiang, China.
PloS one
|May 16, 2025
概括
这项研究旨在在肩膀手术患者中寻找 costoclavicular 椎 - 椎块 (CCB-CPBs) 的最佳罗皮瓦卡因剂量. 目标是确保有效的术后疼痛缓解,同时尽量减少半膜 (HDP).
科学领域:
- 麻醉学 麻醉学
- 区域麻醉地区麻醉
- 疼痛管理 疼痛管理
背景情况:
- 旋转手套受伤很常见,经常进行关节镜修复.
- 间层臂阻塞用于术后止痛,但患半膜的发病率很高 (HDP).
- 骨关节臂 - 椎阻塞 (CCB-CPBs) 提供了可比的止痛效果,降低了HDP风险,但最佳局部麻醉体积至关重要.
研究的目的:
- 确定罗皮瓦卡因在接受关节镜肩部手术的患者中治疗术后疼痛的最佳剂量.
- 为了评估CCB-CPBs的疗效和安全性,使用不同量的罗皮瓦卡因.
- 为了最大限度地降低半膜 (HDP) 的风险,同时确保足够的疼痛控制.
主要方法:
- 前性,单臂,双盲剂量检测研究.
- 招募40名在全身麻醉下进行关节镜肩部手术的患者,使用CCB-CPBs.
- 上下顺序分配设计,以确定局部麻醉剂的体积.
- 主要结局:在麻醉后护理单位 (PACU) 的数值评分表 (NRS) 得分.
- 二次结局:双侧腹膜外流,感觉运动阻断特征,并发症,以及手术内使用芬太尼.
主要成果:
- 将对PACU中的NRS分数进行评估.
- 将监测隔膜功能和阻塞特征.
- 将记录并发症的发生率和芬太尼的使用情况.
结论:
- 这项研究旨在为CCB-CPBs建立最佳的罗皮瓦卡因剂量.
- 这些发现将指导临床实践,以平衡有效止痛和降低HDP风险.
- 这项研究有助于在肩膀手术中制定更安全的术后疼痛管理策略.
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