早期舌头癌的单一高剂量间歇性支臂疗法:系统性审查
Muhammad Kabir Abdulkadir1, Gokula Kumar Appalanaido2, Muhamad Yusri Musa2
1Advanced Medical and Dental Institute, Universiti Sains Malaysia, Kepala Batas, 13200 Penang, Malaysia; Department of Radiography and Radiation Science, Faculty of Basic Clinical Sciences, University of Ilorin, 240213 Ilorin, Nigeria.
概括
高剂量率支臂治疗为早期舌头癌提供了安全有效的治疗方法,实现了高局部控制率并保持了器官功能. 这种方法证明了对患者的显著治疗益处.
科学领域:
- 在瘤学瘤学.
- 辐射瘤学 辐射瘤学
- 手术瘤学手术瘤学
背景情况:
- 支臂疗法是一种有价值的器官和功能保存治疗舌头癌症.
- 高剂量率支臂治疗与低剂量率支臂治疗相比,提供更高的剂量一致性.
研究的目的:
- 审查关于早期舌头癌症的高剂量速率足部支臂治疗的文献.
- 评估治疗特征,结果,毒性和治疗益处.
主要方法:
- 使用PubMed对Medline数据库进行系统审查.
- 关键词包括间歇性支臂疗法和舌头癌症.
- 包括的研究重点是针对早期舌头癌症的专用高剂量速率支臂治疗.
主要成果:
- 分析了涉及305名患者的11篇文章.
- 常见的治疗方法:60Gy分为10个分数,持续5-10天.
- 5年后的局部控制率:65%-100%;存活率:46%-94%.
- 观察到最小的毒性,12%的人经历了死亡.
结论:
- 单独的间歇性高剂量率支架疗法是早期舌头癌症的安全有效选择.
- 较高的局部控制率导致器官功能保持的优势.
- 这种模式代表了早期舌头癌症的可行治疗选择.
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