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Updated: May 5, 2026

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1-尼托烯通过EMPs介导的铁化通过谷氨过氧化酶4触发了 trofhoblast 功能障碍

Shuping Yu1, Kai Wang2, Yan Kang3

  • 1Key Laboratory of Maternal & Fetal Medicine of National Health Commission of China, Shandong Provincial Maternal and Child Health Care Hospital Affiliated to Qingdao University, Jinan, 250014, China; Qilu Institute of Technology, Jinan 250200, China.

Toxicology
|May 16, 2025
PubMed
概括

暴露于1-尼托烯 (1-NP) 会损害血管和胎盘细胞. 它释放有毒的内皮微粒 (EMP),通过抑制GPX4,导致妊娠并发症,从而导致热囊细胞中的铁亡.

关键词:
一-尼特罗皮尔烯 (Nitropyrene) 是一种电磁 EMPs 是一个电磁波.在GPX4中使用GPX4.铁性化 (ferroptosis) 是一种热囊细胞的热囊细胞.

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