相关实验视频
Updated: Jul 19, 2026

10:51
Evaluating Primary Blast Effects In Vitro
Published on: September 18, 2017
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M Tariq Bhatti1, Jeffrey G Moore2, Thomas N Hwang3
1The Permanente Medical Group, Department of Ophthalmology, Kaiser Permanente-Northern California, Roseville, CA, USA.
Survey of ophthalmology
|May 16, 2025
概括
一位最初怀疑患有巨细胞动脉炎的患者在成像显示出轨道和鼻质量后被诊断出可卡因诱导的中线破坏性病变. 这一案例凸显了在中线破坏性病变中考虑药物滥用的重要性.
科学领域:
- 眼科医生 眼科 眼科
- 神经学 神经学
- 毒理学 毒理学 毒理学
背景情况:
- 巨细胞动脉炎 (GCA) 可能会出现轨道和鼻症状,但诊断可能具有挑战性,特别是在负面活检时.
- 中线破坏性病变 (MDLs) 涵盖了一系列影响轨道,鼻和鼻腔的疾病,病因不同.
- 可卡因滥用是MDLs未被认可的原因,通常模仿其他炎症或瘤过程.
研究的目的:
- 介绍一个59岁妇女的病例,最初症状暗示GCA.
- 为了说明与可卡因诱导的中线破坏性病变相关的诊断挑战和成像发现.
- 强调彻底的病史的重要性,包括药物使用,在诊断复杂的轨道和鼻病理方面.
主要方法:
- 临床表现为头痛,双眼视,以及炎症标志物升高.
- 最初的阴性动脉活检和疑似GCA的治疗.
- 检查CT血管图和MRI显示轨道质量和鼻疾病.
- 在ANCA测试和鼻内活检.
- 患者病史显示内鼻可卡因使用.
主要成果:
- 最初的表现模仿了GCA,带有脑周头痛和升高的炎症标志物.
- 图像检测显示,右侧的中枢轨道质量与中枢轨道壁的破坏和鼻鼻模糊.
- 尽管进行了阴性动脉活检和治疗GCA,但症状仍然存在.
- 在确定鼻内可卡因使用后,可卡因诱导的中线破坏性病变的诊断得到证实.
结论:
- 可卡因诱导的中线破坏性病变可以呈现出模仿其他疾病 (如GCA) 的症状.
- 多模式成像对于识别MDLs中的轨道和鼻参与至关重要.
- 包括非法物质使用在内的全面患者病史对于准确诊断和管理破坏性炎症状况至关重要.
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