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Updated: Jul 6, 2026

Peptide:MHC Tetramer-based Enrichment of Epitope-specific T cells
13:58

Peptide:MHC Tetramer-based Enrichment of Epitope-specific T cells

Published on: October 22, 2012

-MHC I 调控机制和干预策略在抗瘤T细胞免疫中

Zhi-Chao Zhang1,2, Ying Shen1,2,3, Yu-Shen Lin1,2

  • 1Innovation Institute for Artificial Intelligence in Medicine, Zhejiang University, Hangzhou, 310018, China.

Acta pharmacologica Sinica
|May 16, 2025
PubMed
概括

瘤细胞通过改变MHC类I (pMHC-I) 的数量和质量来逃避T细胞免疫力. 调节pMHC-I表达为有效的瘤免疫疗法提供了一个有希望的策略.

关键词:
对于T细胞免疫的免疫力.在表观遗传层面调节调节.基因水平调节 基因水平调节免疫疗法 免疫疗法在pMHC-I中,蛋白质水平调节的规定

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