大脑机制是思想抑制控制的基础
Michael C Anderson1,2, Maite Crespo-Garcia3, S Subbulakshmi4
1MRC Cognition and Brain Sciences Unit, University of Cambridge, Cambridge, UK. michael.anderson@mrc-cbu.cam.ac.uk.
Nature reviews. Neuroscience
|May 16, 2025
概括
阻止不必要的想法涉及类似于停止行动的大脑机制,但也涉及独特的途径. 停止记忆检索的缺陷可能会导致精神疾病中的侵入性思维.
科学领域:
- 神经科学是一个神经科学.
- 认知心理学 认知心理学
- 精神病学是一个精神病学.
背景情况:
- 抑制性控制对于调节行为和思想至关重要.
- 右侧前额叶皮质与域一般抑制控制有关.
- 现有的研究主要集中在停止行动上,忽视了思想抑制机制.
研究的目的:
- 审查关于抑制记忆检索作为思想控制模型的研究.
- 识别共享和独特的神经机制的行动与思想的抑制.
- 探索这些机制在侵入性思维和精神疾病中的作用.
主要方法:
- 审查关于抑制控制的现有神经科学和心理学研究.
- 对调查记忆检索停止的神经基础的研究进行分析.
- 检查前时通路和海马体功能的作用.
主要成果:
- 检索停止股份前额机理 (右侧背侧和腹侧) 与行动停止.
- 一个独特的前时路径被招募用于成功的心理控制.
- 海马体的GABAergic抑制调节了对思维过程的前额控制.
结论:
- 共享的前额叶机制支持一个域一般的抑制控制系统.
- 独特的前时路径和海马功能对于思想抑制至关重要.
- 检索停止的缺陷,可能涉及海马体的消抑制,可能是精神疾病中侵入性思维的基础.
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