数据合成中的隐私保护:对生存分析性能的影响
Mareile Beernink1, , Christopher Gundler1
1Institute for Applied Medical Informatics, University Medical Center Hamburg-Eppendorf.
Studies in health technology and informatics
|May 17, 2025
概括
将差异性隐私集成到用于生存分析的合成数据中,影响了准确性. 仔细的模型选择和预处理可以改善结果,其中一种方法实现了超过0.68.6的一致性指数.
科学领域:
- 医疗信息学 医疗信息学
- 数据科学数据科学数据科学
- 生物统计学 生物统计学
背景情况:
- 生存分析对于预测患者的结果至关重要.
- 综合数据与差异性隐私提供了增强的患者保密性.
- 在生存分析的合成数据中平衡隐私和准确性仍然是一个挑战.
研究的目的:
- 调查差异隐私对生存分析合成数据准确性的影响.
- 评估隐私保护与预测性能之间的权衡.
- 确定在生存数据合成中整合差异性隐私的最佳方法.
主要方法:
- 通过使用CTAB-GAN+合成了德国肺癌患者数据集.
- 应用了CoxPH和DeepSurv模型进行生存分析.
- 利用森林小姐用于归算和对分类变量的各种编码技术.
主要成果:
- 不同的隐私预算显著影响了模型的准确性.
- 模型选择和数据预处理提高了准确度高达4.5%.
- 在CoxPH模型中,使用森林小姐归因和一热编码,在差异隐私下实现了超过0.68的一致性指数.
结论:
- 差异性隐私集成对于生存分析数据合成是可行的.
- 在归算和编码方面的方法选择对于保持准确性至关重要.
- 在强大的隐私和可靠的预测能力之间取得平衡是可以实现的.
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