采用 Ontologies:可持续的研究重用生物医学资源本体学
Lea Michaelis1, Sebastian Lobentanzer2,3, Dagmar Waltemath1
1Medical Informatics Laboratory, University Medicine Greifswald, Germany.
Studies in health technology and informatics
|May 17, 2025
概括
采用和调整现有的实体学是可持续数据使用的关键. 保持知识确保本体学保持相关性,支持研究中的FAIR数据原则.
科学领域:
- 生物医学信息学 生物医学信息学
- 数据科学数据科学数据科学
- 科学研究 科学研究
背景情况:
- FAIR原则 (可查找性,可访问性,可互操作性,可重复使用性) 对于科学中可持续的数据使用至关重要.
- 实体学是增强数据互操作性和可重复使用性的重要工具.
- 现有的本体学可能会变得过时或多余,给它们的持续应用带来挑战.
研究的目的:
- 倡导采用和适应现有的本体学.
- 通过一个案例研究来证明这种方法的价值.
- 促进知识文化,维护科学数据.
主要方法:
- 审查FAIR原则和本体论的作用.
- 对生物医学资源本体学 (BRO) 的案例研究分析.
- 讨论本体学适应的过程和好处.
主要成果:
- 采用和调整现有的实体是维护数据互操作性的可行策略.
- 生物医学资源本体学 (BRO) 案例研究说明了这种方法的实际应用和好处.
- 为了长期的数据可持续性,需要一种主动的知识维护文化.
结论:
- 适应现有的本体论,虽然耗时,但对于维护FAIR数据原则至关重要.
- 知识维护确保本体学保持相关性,并支持可持续的科学研究.
- 这种方法提高了科学数据的整体公平性和可重复使用性.
相关概念视频
Ethics in Research
25.3K
Today, scientists agree that good research is ethical in nature and is guided by a basic respect for human dignity and safety. However, this has not always been the case. Modern researchers must demonstrate that the research they perform is ethically sound.
25.3K
Bioequivalence: Overview
1.6K
Pharmaceutical equivalents, by definition, are drug products with the same active ingredient in the same quantities, encapsulated in identical dosage forms, and intended for the same administration routes. These pharmaceutical equivalents are deemed bioequivalent if the bioavailability of the active entity in the drug preparations is similar. Moreover, pharmaceutical equivalents demonstrating bioequivalence are also regarded as therapeutically equivalent. This means that when used as directed,...
1.6K
Sustainable Development
14.7K
As the human population continues to grow and use resources, we must be mindful of our planet’s natural limits. Sustainable development provides a pathway to maintain and improve human life now while also ensuring that future generations will have the resources that they need. The long-term success of sustainability efforts rests on understanding the interplay between human actions and ecological systems.
14.7K
Methods of Documentation I: Source-Oriented Records
1.7K
Source-oriented records, or SOR, are medical record-keeping organized by the data source. The SOR system was first developed in the mid-1900s to organize the growing patient data in hospitals and other healthcare facilities.
In an SOR, each discipline involved in patient care maintains a separate medical record section. This record-keeping method enables easy tracking of patient progress and ensures healthcare staff have access to up-to-date information.
Key Attributes include the following:
In an SOR, each discipline involved in patient care maintains a separate medical record section. This record-keeping method enables easy tracking of patient progress and ensures healthcare staff have access to up-to-date information.
Key Attributes include the following:
1.7K
Ethics and Bioethics
2.6K
Ethics is a philosophical study of moral actions. Ethics attempts to determine what is valuable for individuals and society. It examines the rational justification of moral judgments and analyzes what is morally just, fair, and right. Bioethics is a sub-discipline of applied ethics that analyzes the philosophical, social, and legal issues in life sciences and medicine. Ethical theories serve as a foundation for decision-making and represent the viewpoints from which people seek direction. They...
2.6K
Bioremediation
22.0K
Bioremediation is the use of prokaryotes, fungi, or plants to remove pollutants from the environment. This process has been used to remove harmful toxins in groundwater as a byproduct of agricultural run-off and also to clean up oil spills.
22.0K


